ACTIVITY OF ETANOL EXTRACT OF SNAKE LID LEAVES (Hedyotis corymbosa (L.) Lamk) ON THE GROWTH OF Staphylococcus aureus BACTERIES

Abstract

Hedyotis corymbosa or commonly known as pearl grass is one of the plants that has great potential as a traditional medicine, especially in the treatment of infections. The development of infection drugs is very rapid considering that the resistance rate in several countries continues to increase. Some cases of infection that often occur are skin infections caused by Staphylococcus aureus bacteria. This study aims to test the ability of ethanol extract of snake tongue leaves in inhibiting the growth of Staphylococcus aureus bacteria. This study is an experimental study, consisting of five treatments with three repetitions, using the paper disk method. Samples in the form of snake tongue leaf extract (Hedyotis corymbosa (L.) Lamk) were dissolved with aqua pro injection which was divided into several concentration groups, namely 5%, 10%, and 15%. The test results showed that snake tongue leaf extract was able to inhibit the growth of Staphylococcus aureus bacteria with an average inhibition area of 13.8 mm (5%), 16.7 mm (10%) and 17.4 mm (15%). Statistical analysis through ANOVA testing obtained results that the three concentrations of snake tongue leaf extract (Hedyotis corymbosa (L.) Lamk) have significant differences in inhibiting the growth of Staphylococcus aureus bacteria.